Xgeva medicine 120mg Denosumab cancer spread to bone, hypercalcemia

How much do you need to know about Xgeva 120mg Denosumab ? You do not know where Denosumab 120mg is sold? LP is an address specializing in buying and selling Xgeva 120mg Denosumab in Ho Chi Minh City, Hanoi, Da Nang, Can Tho … and nationwide. Denosumab 120mg is used to treat bone problems such as cancer that has spread to the bone or to treat hypercalcemia.

Xgeva medicine 120mg Denosumab treatment of cancer spread to bone, hypercalcemia

• Brand name: Xgeva
• Other name: Prolia
• Active ingredient: Denosumab
• Manufacturer: AMGEN
• Content: 120mg
• Form: Injectable drug
• Package: Box of 120mg of infusion
• XGEVA Drug Prices: COMMENT below for prices OR Click on the link: https://thuoclp.com/chatFB type “Xgeva”

Indications for use Xgeva 120mg, What is Denosumab ?

• XGEVA 120mg Denosumab is indicated for the treatment of bone problems that can occur with cancer that has spread to the bone or for treating high blood calcium (hypercalcemia) that can occur with cancer.
• Denosumab injection (Xgeva) is used to treat osteoporosis in men and women who have gone through menopause, who cannot or do not respond to treatment with other osteoporosis medications.
• The injection of Denosumab (Xgeva) is also used to treat osteoporosis in men with prostate cancer and in women with breast cancer who are being treated by certain methods that may increase the risk of fractures. bone.
• Denosumab (Xgeva) is used to reduce fractures from certain types of cancer that start in another part of the body but have spread to the bone. Denosumab injection (Xgeva) is also used in adults and some adolescents to treat giant bone cell tumors (GCTB).

Contraindications Denosumab, important information

• This medication guide provides information about denosumab’s Prolia brand. Xgeva is a denosumab brand used to prevent fractures and other bone diseases in people whose tumors have spread to the bone.
• Contraindicated in patients with low blood calcium levels (hypokalemia) and patients with hypersensitivity to the components of the drug.
• Prolia can harm an unborn baby or cause birth defects. Do not use if you are pregnant.

Instructions for use of Denosumab drugs

• Denosumab is injected subcutaneously in the upper arm, thigh, or abdomen, usually by a doctor or nurse at a clinic or hospital.
• When parenteral denosumab (Xgeva) is used to treat osteoporosis or to treat osteoporosis in men with prostate cancer and women with breast cancer, it is usually given every 6 months.
• When parenteral denosumab (Xgeva) is used to reduce metastatic bone fractures into the bone, it is usually given once every 4 weeks.
• When parenteral denosumab (Xgeva) is used to treat massive bone cell tumors, it is usually given every 7 days for the first three doses (on day 1, day 8, and day 15) and after That once every 4 weeks starting 2 weeks after the first three doses.
• Your doctor will give you calcium and vitamin D supplements while you are being treated with the injection form of denosumab.

Caution before using Xgeva

You should not receive Xgeva if you are allergic to denosumab, or if you have low calcium in your blood (hypokalemia).

While you are using Xgeva, you should not receive Prolia, another denosumab brand.

To make sure Xgeva is safe for you, tell your doctor if you:

• kidney disease (or if you are on dialysis);
• a weak immune system (caused by disease or by using certain medicines);
• a history  of hypoparathyroidism  (reduced function of the parathyroid glands);
• a history of   thyroid surgery ;
• a history of surgery to remove a part of the intestine;
• any condition that makes it difficult for your body to absorb nutrients from food (reduced absorption); or
• If you are allergic to latex.

Denosumab can cause bone loss (bone  necrosis  ) in the jaw. Symptoms include  neck pain  or  numbness  , red or swollen gums, loose teeth, gum infection, or delayed healing after dental work.

Osteonecrosis of the jaw may be more likely if you have cancer or receive  chemotherapy  , radiation, or steroids. Other risk factors include coagulation disorders, anemia (low red blood cells), and a dental problem is available.

Denosumab can harm an unborn baby or cause birth defects. Do not use Prolia if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

It is not known whether denosumab can pass into breast milk or if it could harm a nursing baby. This medicine may also slow breast milk production. You should not breast-feed while taking denosumab.

Side Effects Denosumab

Call emergency medical help if possible side effects :  rash , itching, rash; shortness of breath, feeling lightheaded; swelling of face, lips, tongue, or throat.

Call your doctor at once if you:

• new or unusual pain in the thighs, hips, or groin;
• severe pain in a joint, muscle, or bone;
• skin problems such as dryness, peeling, redness, itching, blisters, bumps, oozing, or sheathing; or
• Low blood calcium (hypokalemia) – numbness or lightness around the mouth or in fingers or toes, waist or body spasms, excessive reflexes.

Serious infections may occur during treatment with DeProlia. Call your doctor at once if you have signs of an infection such as  :

• fever  , chills,  night sweats  ;
• swelling, pain, tenderness, heat, or redness anywhere on the body;
• pain or burning while urinating;
• increased or urgent urination;
• severe stomach pain; or
• cough, shortness of breath.

Common side effects may include:

• bladder infection  (painful urination or difficulty urinating);
• back pain  ,  muscle pain  ; or
• pain in your arms or legs.

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Drug interactions

• Before taking Denosumab, tell your doctor or pharmacist:
• If you are allergic to it or if you have any other allergic reaction. This product may contain inactive ingredients, which may cause allergic reactions or other problems.
• The medications you are taking, including prescription and over-the-counter medicines, vitamins, supplements, and herbal products, especially cancer medicines; immunosuppressant medications such as azathioprine (Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), methotrexate (Rheumatrex, Trexall), sirolimus (Rapamune), and tacrolimus (Prograf); or oral steroids such as dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), and prednisone (Sterapred); Your doctor may need to change your medication dose or monitor carefully for side effects

Preserving the drug

• Store in original container at 2 ° C to 8 ° C (36 ° F to 46 ° F). Do not freeze. 
• Before use, bring to room temperature 25 ° C (77 ° F) in the original container (usually takes 15 to 30 minutes); Do not use any other method to warm. 
• Use within 14 days at room temperature. 
• Protection from direct heat and light; Do not store in temperatures> 25 ° C (77 ° F). Avoid strong vibrations.

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Note: Information on Xgeva 120mg Denosumab article for the purpose of sharing reference knowledge, patients are not allowed to use the drug on their own, all information on drug use must be directed by a qualified physician.

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