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Xtandi medicine 40mg Enzalutamide treats prostate cancer
- Brand name: Xtandi 40mg
- Active ingredient: Enzalutamide
- Manufacturer: Astellas
- Content: 40mg
- Form: Capsules
- Package: Box of 112 capsules
- Xtandi Drug Prices: COMMENT below for prices OR Click on the link: https://thuoclp.com/chatFB type “Xtandi”
What is Xtandi medicine? Assign Enzalutamide drug
The drug Xtandi (enzalutamide) is an anti-androgen substance. It works in the body by blocking the action of androgens (male hormones).
Xtandi medicine 40mg is used to treat prostate cancer .
Xtandi may also be used for purposes not listed in this medication guide.
How to use Xtandi medicine?
Take Xtandi exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take Xtandi pills in larger or smaller amounts or for longer than recommended.
You can take Xtandi with or without food. Take the medicine at the same time every day.
Do not crush, break, or dissolve a capsule. Swallow capsules whole.
Prostate cancer is sometimes treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses or medication schedule without your doctor’s advice.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Xtandi dosing information
Usual adult dosage for prostate cancer:
160 mg (four 40mg capsules) orally once a day
Use: castrated prostate cancer metastases
What happens if I miss a dose?
Take the missed dose if you remember it later in the day. Skip the missed dose if it is almost time for your next day’s dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Search to the nearest health facility or call emergency 115
Important information Xtandi medicine 40mg
Although not for use by women, Xtandi can cause birth defects if the mother or father is taking Xtandi medicine. Use condoms and another form of birth control to prevent pregnancy during your treatment, and for at least 3 months after you finish treatment.
Xtandi can cause side effects on your spinal cord. Stop taking Xtandi and call your doctor at once if you have severe low back pain, difficulty walking or standing up, pain or weakness in your lower body, severe numbness and worsening, or tingling , or sudden loss of bladder or bowel control.
Before taking Xtandi tablets
Xtandi may increase the risk of having a seizure. To make sure Xtandi medicine is safe for you, tell your doctor if you have:
- epilepsy or other seizure disorder; or
- a recent head injury, stroke, or brain tumor (within the past 12 months).
Although not for use by women, Xtandi can cause birth defects if the mother or father is taking Xtandi medicine. Do not use Xtandi if you are pregnant.
If you are taking Xtandi and your sexual partner may become pregnant, use condoms and another form of birth control to prevent pregnancy during treatment. Keep using these methods of contraception for at least 3 months after you finish treatment. Tell your doctor right away if pregnancy occurs when either parent has been treated with enzalutamide.
Although Xtandi is not used by women, it is not known whether enzalutamide passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using Xtandi medicine.
What should i avoid while exposed to xtandi?
The Xtandi medicine may make you dizzy, and may cause you to have a seizure or suddenly become unconscious. Be careful if you drive or do anything that requires you to be awake. Severe dizziness can cause falls or other accidents.
Enzalutamide can pass into body fluids (urine, stool, vomit). Caregivers should wear rubber gloves when cleaning a patient’s body fluids, handling contaminated waste or washing or changing diapers. Wash hands before and after removing gloves. Wash soiled clothes and towels separately from other laundry.
Xtandi side effects
Get emergency medical help if you have signs of an allergic reaction to Xtandi: hives; shortness of breath; swelling of face, lips, tongue, or throat.
Xtandi can cause side effects on your spinal cord. Stop taking Xtandi medicine and call your doctor at once if you have:
- severe low back pain, pain or weakness in your lower body;
- trouble walking or standing up;
- severe and worsening numbness or tingling; or
- Sudden loss of bladder or bowel control.
Stop using Xtandi and call your doctor at once if you have:
- seizures (black-out or seizures);
- red or pink urine;
- signs of a lung infection – fever, cough with yellow or green mucus, stabbing chest pain, wheezing, feeling short of breath; or
- signs of swelling in your brain – severe headache, ringing in your ears, vision problems, lack of energy, confusion, weakness.
Your cancer treatments may be delayed or stopped permanently if you have certain side effects.
General Xtandi side effects may include:
- headache, dizziness, turning feeling;
- feeling short of breath, feeling weak or tired;
- increased blood pressure (severe headache, blurred vision, pounding in your neck or ears);
- numbness, burning or tingling sensation under your skin;
- discharge (hot, red, hot feeling);
- back pain, joint or muscle pain, bone pain;
- swelling in your arms or legs;
- loss of appetite, weight loss;
- diarrhea, constipation; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
What other drugs will affect Xtandi?
Xtandi may increase the risk of having a seizure. This effect may be more likely if you also use certain other medications that increase the risk of seizures. Tell your doctor if you are using an antibiotic, antidepressant, asthma medicine (bronchodilator), oral contraceptive or hormone replacement, insulin or oral diabetes medication, a steroid or medication to mental illness treatment.
Many drugs may interact with enzalutamide. This includes prescription and over-the-counter medications, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Xtandi. Give a list of all your medications to any health care provider who treats you.
Scientific information about Xtandi – New drug to treat prostate cancer
A new drug designed to treat advanced prostate cancer has received approval from the U.S. Food and Drug Administration (FDA) on August 31, 2012.
Experts say the drug, branded Xtandi (enzalutamide), has received rapid kidney approval under a priority program that looks at drugs that could potentially promote the treatment of prostate cancer today. by the FDA.
“The need for additional treatment options for prostate cancer is very important in the current period” – Dr. Richard Pazdur, Director of Hematology and Cancer Product Office at the FDA Center for Drug Evaluation and Research, said: “Xtandi is the latest treatment, which has been shown to prolong life for prostate cancer patients.”
Xtandi inhibits the body’s production of the male hormone testosterone – the hormone that stimulates prostate growth. This means that men with recurrent or metastatic prostate cancer using Xtandi will not need hormone or other chemotherapy, the FDA said.
In a study of nearly 1,200 prostate cancer patients, patients on Xtandi were able to extend their life expectancy by an average of 18.4 months, compared to 13.6 months for placebo patients. .
According to the National Cancer Institute, about 242,000 men will be diagnosed with prostate cancer and more than 28,000 will die from this incurable disease this year in the United States.
The side effects that people taking the Xtandi medicine in the study had include: back pain, fatigue, diarrhea, joint pain, headache, dizziness, and high blood pressure. About 1% of people using Xtandi have to stop taking the drug because of seizures, the FDA said.
Xtandi will be marketed by the Astellas Pharmaceutical Company in Northbrook, Illinois, and the Medivation Company in San Francisco (USA).
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Drug Xtandi 40mg Enzalutamide cost?
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Note: Information about Xtandi 40mg Enzalutamide drug for the purpose of sharing knowledge, patients are not allowed to use the drug on their own, all information on drug use must be directed by a qualified physician.
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Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Pharmacy.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Medical Certificate:
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.
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