Valcyte medicine 450mg Valganciclovir Retinitis – Valcyte drug price

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Valcyte medicine 450mg Valganciclovir Retinitis

• Trade name: Valcyte
• Active ingredient: Valganciclovir
• Content: 450mg
• Form: Tablets
• Package: 1 vial of 60 capsules
• Manufacturer: Roche
• Valcyte Medication Price: COMMENT below for
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What is Valcyte 450mg? Indications & uses  

Valcyte belongs to a group of medicines, which work directly to prevent the development of viruses. In the body the active ingredient in tablets, valganciclovir, was renamed ganciclovir.

Ganciclovir prevents a virus called cytomegalovirus (CMV) from multiplying and invading healthy cells. In patients with weakened immune systems, CMV can cause an infection in the viscera. This can be life threatening.

The drug Valcyte is used

• for the treatment of CMV-infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). CMV-infection of the retina of the eye can cause vision problems and even blindness.
• to prevent CMV infection – in adults and children who are not infected with CMV and who have received organ transplants from someone who has been infected by CMV.

Dosage of Valcyte 450mg medicine 

Adults:

Prevention of CMV disease in transplant patients

• Start taking this medicine within 10 days after organ transplantation.
• The usual dose is 2 tablets / day. Continue drinking within 100 days after organ transplantation. If you have received a kidney transplant, your doctor may prescribe it for up to 200 days.

Treatment of CMV active retinitis in AIDS patients

• Usual dose: 2 capsules daily for 21 days (three weeks). Do not take more than 21 days unless directed by your doctor, as this may increase the risk of side effects.
• Long-term treatment to prevent active recurrence of AIDS prevention

Patients with CMV retinitis

• Usual dose: 2 capsules / day. Take medication regularly at the same time every day. Your doctor will advise you how long you should continue taking Valcyte. If your retinitis worsens while you’re on this dose, your doctor may tell you to repeat induction (as above) or may decide to give you a different medication to treat. Treatment of CMV infections.

Elderly patients

• Valcyte has not been studied in elderly people, patients.

Patients with kidney problems

• If your kidneys aren’t working properly, your doctor may teach you to take fewer pills every day or just to take your pills on some days each week. It is very important that you only take the prescribed amount according to your doctor’s prescription.

Patients with liver problems

• Valcyte has not been studied in patients with liver problems.

Use in children and adolescents

• Prevention of CMV disease in transplant patients should start taking this medication within 10 days of their transplant. Certain doses will vary according to the size of the child and should be taken once daily. Your doctor will decide the most appropriate dose based on your child’s height, weight and kidney function. You should continue with this dose for up to 100 days. If your child has received a kidney transplant, your doctor may advise you to take these doses for 200 days.

Forgot to take Valcyte medication?

If you forget to take the medicine, wait until the next dose, do not take double the number of doses.

Do not stop taking Valcyte without your doctor’s instructions.

Overdose

If you take more Valcyte than you should contact your doctor or hospital right away if you have taken, or think you have taken, more pills than you need. Taking too many medicines can cause serious side effects, especially affecting your blood or kidneys.

You may need hospital treatment.

How to use Valganciclovir medicine

• Always take this medication exactly as your doctor or pharmacist told you. Check with your doctor or pharmacist if you are unsure.
• You should swallow the entire tablet with food whenever possible. Do not break or crush the tablet.
• If you accidentally touch the damaged tablet, wash your hands well with soap and water. If any powder from the tablet gets into your eyes, wash your eyes with sterile water or clean water if you do not have sterile water.

For children unable to swallow

• Valcyte film-coated tablets, Valcyte powder for oral solution may be used.

Watch video Valcyte medicine 450mg (Valganciclovir medicine) 

Note before taking Valcyte

Do not take valcyte if:

• If you are allergic to valganciclovir or any of the other ingredients of this medication
• If you are allergic to ganciclovir, acyclovir or valaciclovir, it is a medication used to treat other viral infections.
• If you are breastfeeding.

Warnings and precautions

Talk to your doctor or pharmacist before taking valcyte.

Take special care when taking Valcyte

• If you have a low number of white blood cells, red blood cells or platelets (small cells that participate in blood clotting) in your blood.

Your doctor will perform blood tests before you start taking valcyte and more tests will be done while you are taking it.

• If you are undergoing radiation therapy or on dialysis
• If you have a problem with your kidneys.

Your doctor may need to prescribe a reduced dose for you and may need frequent blood tests during treatment.

• If you are taking ganciclovir tablets and your doctor wants you to switch to Valcyte tablet. It is important that you do not take more than the number of pills prescribed by your doctor or you may be at risk of an overdose.

Pregnancy, lactation and fertility

• You should not use Valcyte if you are pregnant unless recommended by your doctor.
• If you are pregnant or plan to become pregnant you must tell your doctor. Taking Valcyte while you are pregnant can harm your unborn baby.
• Do not take Valcyte if you are breast-feeding a baby. If your doctor wants you to start treatment with Valcyte, you must stop breastfeeding before you start having to take your medication.

Drive and use machines

• Do not drive or use any tools or machines if you feel dizzy, tired, shaky or embarrassed while taking this medication. Ask your doctor or pharmacist for advice before taking any medicine.

Drug interactions Valcyte and other drugs

Tell your doctor or pharmacist if you are taking, have recently taken, or can take any other medicines, including medicines obtained without a prescription.

If you take other medications at the same time as taking Valcyte the combination may affect the amount of drug that enters your blood stream or may cause harmful effects. Tell your doctor if you are taking medicines that contain any of the following:

• imipenem-cilastatin (an antibiotic). Taking this with Valcyte may cause seizures (fits)
• zidovudine, didanosine, lamivudine, tenofovir , abacavir, emtricitabine or similar drugs used to treat AIDS
• ribavirin, pegylated interferon, adefovir and entecavir for the treatment of hepatitis B / C
• probenecid (a drug against gout).

Taking probenecid and valcyte at the same time can increase the amount of ganciclovir in your blood

• mycophenolate mofetil (use after transplanting)
• vincristine, vinblastine, adriamycin, hydoxyurea or similar types of drugs for cancer treatment
• Use cidofovir or foscarnet against infectious viruses
• trimethoprim, combination trimethoprim / Sulphate and dapsone (antibiotics)
• pentamidine (medicine to treat parasite or lung infection)
• flucytosine or amphotericin B (antifungal agent)

Drug interactions Valcyte with food

• Valcyte should be taken with food. If you are unable to eat for any reason, you should still take the same dose of Valcyte as usual.

Valcyte side effects 450mg

Like all medicines, this drug can cause side effects, not everyone has side effects.

Allergic reaction

1 in 100 people may have a sudden and severe allergic reaction to valganciclovir (anaphylactic shock). STOP taking Valcyte and go to the nearest hospital if you experience any of the following:

• Rashes, itchy rashes (rash)
• Sudden swelling of the throat, face, lips and mouth can cause difficulty swallowing or breathing
• Sudden swelling of hands, feet or ankles.

The side effects that have occurred during treatment with valganciclovir or ganciclovir are given below.

Very common side effects (> 1 in 10 people)

• Effects on blood: reducing the number of white blood cells in the blood (leukopenia) – which will make you more likely to become infected, reduce the pigmentation in the blood carrying oxygen (anemia) – can cause fatigue Fatigue and shortness of breath when you exercise
• Respiratory effects: feeling short of breath or short of breath (shortness of breath)
• Effects on stomach and digestive system: diarrhea T

Uncommon side effects (1-10 / 1000)

• Effects in the center: changes in the normal heart rate (arrhythmia)
• Effects on circulation: low blood pressure, can make you feel lightheaded or faint
• Effects on blood: a decrease in the production of blood cells in the bone
• marrow
• Effects in the nerves: tremor or tremor
• Effects in eyes: redness, swelling of the eyes (conjunctivitis), abnormal vision
• Effect in the ear: deaf
• Gastrointestinal or gastrointestinal effects: swollen stomach, mouth ulcers, pancreatitis, where you may notice severe pain in your abdomen and back
• Skin effects: hair loss, itching rash or swelling, dry skin
• Effects in the kidneys: blood in urine, kidney failure
• Hepatic effects: an increase in liver enzyme called alanine aminotransferase which will only be seen in blood tests
• Effects on fertility: infertility in men
• impact on mood or behavior: there are abnormal changes in mood and behavior, loss of contact with reality such as hearing voices or seeing things that are not there, feelings of agitation

Rare side effects (may affect 1-10 users in 10,000)

• Effects on blood: failure of producing all types of blood cells (red blood cells, white blood cells and platelets) in bone marrow
• Separation of the inner lining of the eye (retinal detachment) has only occurred in AIDS patients treated with Valcyte for CMV infection.
• Other side effects in children and adolescents
• Side effects reported in children and adolescents are similar to those reported for adults.

Valcyte contains common side effects (may affect 1-10 users at 100)

• Effects on blood: the decrease in the number of white blood cells (blood cells against infection) in the blood (leukopenia), a decrease in the number of platelets in the blood: may cause bruising and bleeding, reducing the number of several types of blood cells at the same time (pancytopenia)
• Nervous system effects: headache, difficulty sleeping (insomnia), strange taste (dysgeusia), becoming less sensitive to touch (hypoaesthesia), thorns or tingling of the skin, loss of sensation in hands or feet ( peripheral neuropathy), dizziness, convulsions

• Effects in the eyes: eye pain, swelling in the eyes (edema), separation inside the lining of the eye (retinal detachment), visible floaters
• Effects in the ear: ear pain
• Respiratory effect: cough
• Gastrointestinal and gastrointestinal effects: feeling and ill, abdominal pain, constipation, wind, indigestion, difficulty swallowing
• Skin effects: dermatitis, itching, sweating at night
• Impact on muscles, joints or bones: back pain, pain in muscles or joints, stiff muscles, muscle cramps
• infection: oral fungal infection (oral candidiasis), infection caused by bacteria or viruses in the blood, cellulitis, inflammation or infection of the kidney or bladder
• Hepatic effects: increased in some liver enzymes, which will only be seen in blood tests
• Renal effects: changes in the normal working of the kidneys
• Effects on eating: appetite, loss of weight
• General effects: fatigue, fever, pain, chest pain, weakness, feeling unwell
• impact on mood or behavior: depression, anxiety, confusion, thinking abnormalities

Preserving the drug Valcyte

• Keep out of reach of children.
• Do not use the medicine after the expiry date, which is stated on the label and carton package after the expiry date, referring to the last day of that month.
• The drug is stored at temperatures below 30 * C.
• Do not throw away any medicine through sewage or household waste. Ask your pharmacist how to dispose of medicines you are no longer using. These measures will help protect the environment.

Packaging and composition

• Active ingredient: 450 mg Valganciclovir, currently 496.3 mg valganciclovir hydrochloride.
• Other ingredients (excipients qs): Povidone K30, Crospovidone, microcrystalline cellulose and stearic acid. The film’s components are hypromellose, titanium dioxide (E171), macrogol 400, iron oxide red (E172) and polysorbate 80.
• Package: Bottle of 60 film-coated tablets.

This medicinal product is authorized in the member states of EEA under the following name:

• Valcyte: Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxemburg, Malta, Netherlands, Norway, Poland, Romania, Slovak Republic, Slovenia, Spain, Sweden, United Kingdom
• RoValcyte : France, Portugal

Source: index-china.com

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