What is Xeloda medicine 500mg Capecitabine – Xeloda drug price

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Xeloda medicine 500mg Capecitabine medicine to treat colorectal cancer, breast cancer, stomach cancer

1. 1. Brand name: Xeloda 500mg
   2. Active ingredient: Capecitabine
   3. Manufacturer: ROCHE
   4. Content: 500mg
   5. Form: Tablets 
   6. Package: Box of 120 tablets
   7. Xeloda Drug Prices: COMMENT below for prices OR Click on the link: https://thuoclp.com/chatFB type “Xeloda”

What is Xeloda?

1. Xeloda (capecitabine) belongs to a group of medicines called antiallergic drugs
2. Xeloda is used to treat colon cancer, and breast or colorectal cancer has spread to other parts of the body.
3. Xeloda is often used in combination with other cancer medications or radiation treatments.

Indications for use of the drug

1. For adjuvant treatment of patients after stage III colon cancer surgery
2. Colon or rectal cancer has spread to other parts of the body.
3. The first treatment of advanced gastric cancer is combined with platinum therapy
4. Combined with docetaxel to treat patients with metastatic breast cancer or local progression after failure in cytotoxic chemotherapy. Previous therapy should include an anthracycline.
5. Treatment of patients with metastatic or locally advanced breast cancer after failure of taxan and chemotherapy regimen containing anthracycline or not indicated for anthracycline therapy.

Dosage and instructions for use of Xeloda

Monotherapy

• Colorectal cancer, breast cancer 1250 mg / m2, 2 times / day (morning, evening) x 14 days, followed by 7 days off.
• Combination treatment: Initial breast cancer 1250 mg / m2, 2 times / day x 2 weeks, combination with docetaxel, then leaves 1 week off;
• Stomach cancer, colorectal cancer 800-1000 mg / m2 / time x 2 times / day x 2 weeks, then 7 days off or 625 mg / m2 / time x 2 times / day with continuous treatment .

How to use: Should be taken with food: Take with water within 30 minutes after eating. DPD shortage. Severe hepatic / renal impairment.

Precautions before using Xeloda drug

You should not use Xeloda if you are allergic to capecitabine or fluorouracil (Adrucil).

To make sure Xeloda is safe for you, tell your doctor if you have any of the following:

• kidney disease;
• bleeding or blood clotting disorders such as haemorrhage;
• liver failure;
• history of coronary artery disease; or
• if you take blood thinners (warfarin, Coumadin, Jantoven).

Do not use Xeloda if you are pregnant. It can harm an unborn baby.

Use birth control to prevent pregnancy while you are taking Xeloda, whether you are male or female. Tell your doctor if pregnancy occurs during treatment.

It is not known whether capecitabine passes into breast milk or whether it could harm a nursing baby. You should not breast-feed while you are taking Xeloda.

Xeloda 500mg side effects 

Get emergency medical help if you have signs of an allergic reaction to Xeloda: hives; shortness of breath; swelling of your face, lips, tongue or throat.

Call your doctor right away if you have:

1. fever above 100.5 degrees;
2. nausea, loss of appetite, eating less than usual, vomiting (more than once in 24 hours);
3. severe diarrhea (more than 4 times per day, or at night);
4. blisters or ulcers in the mouth, red or swollen gums, trouble swallowing;
5. pain, redness, swelling, blistering, or peeling of skin on your hands or feet;
6. symptoms of dehydration – feeling very thirsty or hot, unable to urinate, excessive sweating, or hot and dry skin;
7. heart problems: chest pain or pressure, irregular heartbeat, difficulty breathing even with light exertion, swelling or rapid weight gain;
8. kidney problems: little or no urination; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;
9. liver problems: nausea, upper stomach pain, itching, feeling of tiredness, loss of appetite, dark urine, clay-colored stools, jaundice;
10. low blood cell count: fever or other flu symptoms, cough, skin sores, pale skin, easy bruising, unusual bleeding, feeling lightheaded, tachycardia; or
11. severe skin reaction: fever, sore throat, swelling in the face or tongue, burning in the eyes, skin pain, then a red or purple skin rash that spreads especially in the face or upper body and causes blisters and sloughing.

Common Xeloda side effects may include:

1. stomach pain or discomfort, constipation;
2. feeling tired;
3. mild skin rash; or
4. numbness or tingling in your arms or legs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Drug interactions

Before starting treatment, tell your doctor or pharmacist if you are taking, have recently taken or may be taking any other medicine. This is extremely important, as taking more than one medication at the same time can reinforce or weaken the effect of the medication.

You need to be especially careful if you are using any of the following medicines:

1. gout medication (allopurinol),
2. blood thinners (coumarin, warfarin),
3. some antiviral drugs (sorivudine and brivudine),
4. seizure or tremor medication (phenytoin),
5. interferon alpha,
6. radiotherapy and some drugs used to treat cancer (folinic acid, oxaliplatin, bevacizumab, cisplatin, irinotecan),
7. Drugs used to treat folic acid deficiency.

Causes of colorectal cancer

The cause of colorectal cancer is not known exactly, but people with certain risk factors are more likely to develop colorectal cancer than others. Some risk factors are as follows:

1. Age: Colorectal cancer usually occurs with older people, the older they are (usually 40 or older), the greater the chance of getting the disease. About 80% of colorectal cancer cases are detected at the age of over 60 years.
2. Diet and activities : People who eat more fat, protein, less fiber and fresh fruits increase the likelihood of disease. Sedentary people and obese people are also at higher risk.
3. History of precancerous lesions: such as colorectal polyps (especially for polyps larger than 2 cm), history of chronic colorectal inflammation, Crohn’s disease, persistent dysentery syndrome.
4. History of cancer: A person who has had colorectal cancer may develop colorectal cancer a second time. In addition, women with a history of ovarian, uterine (endometrial) cancer, or breast cancer are at a slightly higher risk of developing colorectal cancer.
5. Family history of colorectal cancer: If someone in the family has a colorectal cancer, especially close blood relationships, the risk of getting sick with family members increases. However, if only one close relative has had colorectal cancer at age 65, the risk increases slightly.
6. Genetic status: Family history of inherited syndromes such as familial polyps, non-hereditary polyps are dozens of times more likely than families without this syndrome

Scientific information about Xeloda medicine 500mg 

Xeloda 500mg can be used at home. Compared with intravenous drug treatments, Xeloda makes treatment uninterrupted and requires less hospitalization. The drug has just been approved by the US Food and Drug Administration (FDA). In the body, when combined with an enzyme, Xeloda turns into 5-FU, a cancer drug that has been used for many years.

The drug was first approved by the FDA in May 1998 to treat metastatic breast cancer. A 30-week study from the University of Texas (USA) shows that, compared with the classical method, the treatment effect of Xeloda is equivalent, while the side effect is less. The main side effects of the drug are diarrhea, nausea and vomiting.

Surgical treatment of colon cancer with Xeloda Medicine (Capecitabine)

• In fact, so far no medicine has been recognized as effective for this disease. The 5-year survival rate after surgery is 90% if the cancer is in the gut. 50% if the cancer has eaten through the wall of the intestine, not eaten into the lymph nodes, 30% when the tumor has eaten into the lymph nodes and only 10% if the cancer has spread into the internal organs, such as the liver and lungs.
• According to Dr. Khoo Kei Siong, senior advisor on oncology and treatment at Gieneagles Hospital (Singapore), tumor removal surgery is optimal for this type of cancer and then therapies are applied. Valence. The risk of surgery (such as bleeding in connective tissue or infection) if carried out by a surgical specialist is reduced by 50-60%.
• After tumor removal surgery, chemotherapy may not be needed. This depends on the stage at which the patient is suffering from cancer. In stage II and III of the disease, the patient must be chemotherapy to increase resilience. In stage IV, chemotherapy stops the growth of cancer cells. Do not use radiation therapy for colon cancer because radiation can easily infect the abdominal organs.
• Recently, new drugs for colon cancer chemotherapy are not only more effective, but also have fewer negative side effects. Therefore, chemotherapy is the safest method. Oxaliplatin, Irinotecan, Cetuximab (Erbitux) and Acizumab (Avastin) are new effective drugs for chemotherapy, some of which do not cause hair loss.
• In particular, recently has the first tablet of metastatic colon cancer called Xeloda (Capecitabine) , with a dose to be taken every 2 days at home. Research at the University of Texas (USA) shows that when you enter the body, the drug combines with an enzyme to turn into 5-FU – a cancer treatment drug that has been used for many years. The efficacy of Xeloda is comparable to that of other chemotherapy drugs, while the side effects are minimal, resulting in uninterrupted treatment and no hospitalization.

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• How much does Capecitabine Xeloda cost 500mg?
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Note: Information about Xeloda 500mg Capecitabine article for the purpose of sharing knowledge for reference only, patients are not allowed to use the drug on their own, all information on drug use must be directed by a qualified physician.