Drug information Topamax for the treatment of epilepsy
|Content||15mg, 25mg, 50mg, 100mg|
|Pack||box of 60 tablets|
What is Topamax 25mg Topiramate?
Topamax 25mg contains the main active ingredient Topiramate 25mg. The drug belongs to a class of drugs called antiepileptic drugs.
medicine is indicated for the treatment of partial seizures with or without secondary generalization. It is also used for the prevention of migraine in adults after the effectiveness of other treatments has been thoroughly evaluated.
What is topiramate’s mechanism of action ?
Topiramate belongs to a class of drugs called sulfamate-substituting monosaccharide anticonvulsants or antiepileptic drugs (AEDs). A drug class is a group of drugs that work in a similar way. These drugs are often used to treat similar conditions.
It is not known exactly how this medicine works. It’s thought to work on certain chemicals, channels, receptors, and enzymes in your brain to help control seizures and prevent migraines.
What is Topamax used for?
- Treat certain types of seizures (without using other medications). The seizures treated were partial-onset seizures and primary generalized tonic-clonic seizures.
- Treatment of certain types of epilepsy in combination with other drugs. The seizures treated were partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with lennox-gastaut syndrome.
- medicine is also used to prevent migraines.
Who should not take Topamax?
- medicine can be taken by adults and children 2 years of age and older.
- Hypersensitivity to Topiramate or any ingredient of Topamax 25mg.
- Not intended for use by pregnant women and women of childbearing age who are not using suitable contraceptive methods.
Dosage and how to use Topamax?
Dosage of the drug
It is common to start Topamax at a low dose of 25mg to 50mg per day. This will be increased over the next few weeks to the usual doses for:
- Epilepsy: 100mg to 200mg per day, taken 2 times;
- Seizures (if you take a seizure medicine other than Topamax): 200mg to 400mg daily in 2 doses;
- Migraine: 50mg to 100mg, taken 2 times.
In children, the dose will depend on your child’s weight. Your doctor will be able to give the right dose to your child.
How to take medicine
- It is usually recommended to take the medicine twice a day. You can take Topamax medicine at any time of the day, but try to take your dose at the same time each day.
- Topamax 25mg tablets can be taken with or without food. Swallow your tablet whole with a glass of water. Don’t chew them.
- medicine can be swallowed whole or they can be opened and sprinkled with a teaspoon of soft food, like porridge or yogurt.
What to do if a dose of Topamax is missed?
- If you forget to take a dose, take it as soon as you remember.
- If it is less than 8 hours before your next dose, it is better to skip the missed dose and take your next dose as usual.
- Do not take 2 doses at the same time to make up for a missed dose.
- If you miss a dose often, it may help to set an alarm to remind you.
- You can also ask your pharmacist for advice on other ways to help you remember to take your medicine.
What to do if overdose?
Ask your doctor for advice immediately. Taking too much Topamax 25mg can lead to serious side effects. Call your doctor at once if you overdose on this medicine, reactions such as:
- Feeling dizzy or drowsy;
- Having trouble talking;
- Blurred vision;
- Feeling confused or changing your behavior.
Precautions while you are taking Topamax
You should not use medicine long-term if you have problems with high blood acids and are also taking metformin for diabetes. To be on the safe side, tell your doctor if you have ever:
- Glaucoma or other eye problems;
- Diabetes, or metabolic acidosis;
- Kidney disease, kidney stones or dialysis;
- Lung disease, breathing problems;
- Eating disorder;
- Liver failure ;
- Soft or brittle bones ( osteoporosis , osteomalacia );
- Growth disorder.
The active ingredient Topiramate found in Topamax can increase the acidity of your blood (metabolic acidosis). This can weaken your bones, cause kidney stones or cause growth problems in children, and be harmful to an unborn baby.
The use of Topamax during pregnancy will increase the risk of birth defects for the baby, such as: cleft lip, cleft palate. The use of drugs that also cause convulsions during pregnancy can be harmful to both mother and baby. You should use safe contraception while taking the drug.
Health conditions may affect the use of the product. Some interactions can make a medical condition worse or make the medication less effective. Please inform your doctor about your current health condition before using this medicine.
Health conditions that may affect how Topamax work include:
- Glaucoma or other eye problems;
- Diabetes or a history of metabolic acidosis;
- Have kidney disease, or have a history of kidney stones, or are on dialysis;
- Have severe breathing problems;
- Have a history of mental illness, depression, suicidal thoughts or behavior;
- Liver disease;
- Growth disorders;
- Soft or brittle bones (osteoporosis, osteomalacia);
Topamax drug side effects
Common side effects of Topamax: feeling nauseous, feeling drowsy, dizzy or tired, diarrhea, feeling pressured, loss of appetite, or weight loss.
Serious side effects: blurred vision, trouble seeing and eye pain, pain in your back, abdomen, or side, burning sensation when you urinate, cloudy or smelly, feeling drowsy, loss of appetite, heartbeat irregularity and fainting, thinking your child is not sweating.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
What other drugs may interact with Topamax?
There are a number of medications that can interfere with how Topamax works.
Tell your doctor if you are taking any of these medicines:
- Medicines used to treat diabetes, such as: metformin, glibenclamide, and pioglitazone.
- Medicines used to treat depression or anxiety, such as: venlafaxine and amitriptyline.
- Medicines to treat heart disease or blood pressure, such as: diltiazem, hydrochlorothiazide, and propranolol.
- Antipsychotics, such as: risperidone.
- Any other seizure medicine.
Interaction with food, drink
Topamax 25mg may interact with certain foods and alcoholic beverages, change how the medicine works or increase the risk of serious side effects. Therefore, consult your doctor about eating, drinking, and smoking while taking this medicine.
Preservation of drugs
- Store the medicine in a cool, dry place, avoid direct sunlight and avoid moisture.
- The suitable temperature for drug storage is < 25°C.
- Keep the medicine out of reach of children and young children.
- Note that unused medicine should not be thrown into household waste because this may cause environmental pollution. Therefore, it should be treated before being released into the environment.
How much does Topamax cost? Where to buy medicine?
How much is the price of Topamax 25mg Topiramate? Please COMMENT below or Contact 0933049874 (Zalo/ Facebook/ Viber/ Whatsapp) to buy and sell brand-name drugs in Ho Chi Minh City, Hanoi, Da Nang City, Can Tho City,… nationwide.
The above article is for reference only and is not a substitute for medical diagnosis or treatment. Readers should only follow the instructions of the doctor who is treating you, Index-China disclaims responsibility if problems occur.
Reputable source ThuocLP Vietnamese: Topamax medicine 25mg Topiramate treatment to prevent epilepsy
Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Pharmacy.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.