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Sabril medicine 500mg Vigabatrin 100 tablets Antiepileptic
- Brand name: Sabril 500mg
- Active ingredient: Vigabatrin
- Manufacturer: Sanofi Aventis
- Content: 500mg
- Form: Tablets
- Package: 10 latitudes x 10 tablets = 100 tablets
- Sabril Drug Prices: COMMENT at the end of the article for prices OR Click on the link: https://thuoclp.com/chatFB type “Sabril”

Introducing Sabril 500mg medicine
- Vigabatrin is an anti-epileptic drug that inhibits the catabolism of gamma aminobutyric acid by irreversibly inhibiting gamma aminobutyric transaminase.
- Vigabatrin is an anticonvulsant. It is thought to work by preventing the collapse of a natural calming substance (GABA) in the brain. Antiepileptic drugs have been associated with an increased risk of developmental disorders and birth defects.
Use Vigabatrin 500mg
- Vigabatrin is used to treat seizure disorder or commonly called epilepsy. Its works by reducing the number of seizures in adults and children were able to control their seizures with other treatment.
- Vigabatrin is also indicated for the use of immunotherapy in generalized secondary tonic clonic, with partial seizure and spasms in children due to western syndrome. Vigabatrin is also used to treat epilepsy in succinic semialdehyde acid deficiency, which is a congenital neurotransmitte.
Contraindications to Sabril
This drug is contraindicated for patients who are planning to become pregnant or are pregnant. Also it is contraindicated for patients with hypersensitivity of any components and components of the drug.
Dosage and usage of Sabril
- This drug is should be given twice a day for about 500 mg. Take this medication by mouth with or without food.
- If your body likes this medication, your doctor may increase the dose of this medicine. The right dose of this medicine will be provided by your doctor if you have doubts about this dosage so your doctor has the right to give your dose.
- Please talk to them if you are using any of these anti-epileptic medications.
Important note
- Before taking this medication, you must know to yourself if you have any history in the following ways: eye problems such as glaucoma, macula, degeneration and optic nerve problems.
- Do not start, stop or change any of this medicine if you have not checked with your doctor. It is very important for women with epilepsy to speak with the doctors responsible for treating their epilepsy before pregnancy. See the expiry date before taking this medicine.

Side effects of Sabril
Get emergency medical help if you have signs of an allergic reaction to Sabril (rash, difficulty breathing, swelling of your face or throat) or severe skin reaction (fever, sore throat, stinging eyes, skin pain , red or purple skin rash with blistering and peeling.
Taking vigabatrin can cause permanent vision loss. Tell your doctor right away about any changes in your vision. If your child is taking Sabril: Tell your doctor right away if your child shows signs of changes in vision, such as hitting objects or being easily startled or surprised.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, thinking about committing suicide or hurting oneself.
Call your doctor right away if you have:
- convulsions increased or worsened;
- Any changes in your vision, no matter how slight;
- abnormal or involuntary eye movements;
- Babies taking vigabatrin: severe drowsiness, fussing, or eating problems;
- numbness, tingling, or burning pain in the arms or legs;
- weight gain;
- signs of ear infection: fever, ear pain or a feeling of fullness, difficulty hearing, discharge from the ear, fussing in the child;
- Low red blood cells (anemia): pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Some babies treated with Sabril have had abnormal brain changes seen on magnetic resonance imaging (MRI). It is not known whether these changes are due to vigabatrin or if they are harmful. Tell any doctor who treats your baby that the child is taking this medication.
Common Sabril side effects may include
- blurred vision or other eye problems;
- drowsiness, dizziness, feeling tired;
- problems with walking or coordination;
- run;
- aggressive behavior;
- confusion, problems with thinking or memory;
- weight gain;
- athritis;
- cold symptoms such as stuffy nose, sneezing, sore throat;
- Infants: fussy, ear infections, cough, shortness of breath.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
The FDA approved Sabril for the treatment of epilepsy in young children
- Sabril oral solution (vigabatrin) is approved by the FDA for the treatment of epilepsy in children from 1 month to 2 years of age. Sabril is the first drug approved by the United States for treating disorders that usually occur at the first year of life (usually occurs in the 4th to 8th month).
- Sabril (vigabatrin) – an approved oral tablet for the treatment of complex types of local seizures unresponsive to previous treatments in adults (in combination with other drugs).
- According to Rurssell Katz, MD, Head of the Neuroscience Group at the FDA Center for Evaluation and Evaluation of Medicines, “Epilepsy reduces neurological function and lowers the quality of life. Seizures in children are very serious, and the approval of this product provides an additional treatment option. ”
- Using Sabril may affect vision. Peripheral visual loss leads to impaired vision. This risk increases with the dose and duration of use, but even the use of Sabril at the lowest dose can affect vision. Therefore, checking eyesight during medication is mandatory. Because of the risk of irreversible vision loss, this medication is limited to some cases.
- Sabril is a rare drug for the treatment of epilepsy in young children. In the United States, drugs that fall into the category are rarely studied to treat fewer than 200,000 people. Rare drug policies provide incentives for drug research and development companies to treat rare conditions or conditions. Sabril is manufactured by Lundbeck Inc. of, Deerfield, Ill.
Storing and preserving drugs Vigabatrin
- This medicine can be stored at room temperature, between 68-77 degrees F.
- This medication can harm your children; Keep this medicine out of their reach.
- Also this medication can be harmful to our environment, if you want our environment to be clean always throw this medication in an appropriate disposal place. Do not wash it in the toilet.

Source: index-china.com
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Note: Information about Sabril 500mg Vigabatrin medicine for the purpose of sharing knowledge for reference only, patients are not allowed to use the drug themselves, all information on drug use must be under the direction of a qualified physician.
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Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Pharmacy.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Medical Certificate:
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.
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