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Femara medicine 2.5mg Letrozole adjuvant treatment of early breast cancer
- Brand name: Femara 2.5mg
- Active ingredient: Letrozole
- Manufacturer: NOVARTIS
- Content: 5mg
- Form: Tablets
- Package: Box of 30 tablets
- Femara Drug Prices: COMMENT below for prices OR Click on the link: https://thuoclp.com/chatFB type “Femara”

What is femara? Letrozole treat what disease?
- Femara (letrozole) reduces estrogen levels in postmenopausal women, slowing the growth of certain types of breast tumors that require estrogen to multiply in the body.
- Femara is used to treat breast cancer in postmenopausal women. It is usually prescribed to women who have been taking tamoxifen (Nolvadex, Soltamox) within 5 years.
- Femara may also be used for purposes not listed in this medication guide.
Indications for treatment
- Postmenopausal women: adjuvant treatment of early breast cancer, positive hormone receptor.
- Adjuvant treatment of early stage breast cancer has been standardized adjuvant therapy with tamoxifen.
- First-line therapy for hormone-dependent advanced breast cancer.
- Advanced breast cancer has been treated with anti-estrogen drugs.
- Pre-surgical treatment of breast conservation for localized breast cancer with a positive hormone receptor.
Femara is used for
- Femara is often used after surgery to reduce the risk of breast cancer returning or spreading.
- If you are undergoing chemotherapy or radiation, your doctor will tell you when to start Femara.
- Femara can sometimes be used as the first treatment for breast cancer, for example when surgery is not appropriate or it needs to be postponed. It is sometimes given before surgery to shrink a larger breast cancer.
- Femara can also be used to treat returned breast cancer. It can also be used to treat breast cancer that has spread to another part of the body (secondary breast cancer), when it is often taken with another drug.
Femara dosage information
Usual adult dosage for breast cancer:
- For use as first-line treatment of menopausal women with aggressive receptors or advanced breast cancer hormone at site of disease or metastatic unknown hormone receptor.
- Femara is also indicated for the treatment of advanced breast cancer in postmenopausal women with the progression of the disease after anti-estrogen therapy: 2.5 mg orally 1 tablet / day without regard to meals.
- In patients with advanced disease, Letrozole treatment should continue until tumor progression is evident.
Usual Adult Dose for Breast Cancer – Complementary:
- For use as extended adjuvant treatment of early-stage breast cancer in postmenopausal women who have received 5 years of tamoxifen adjuvant treatment: 2.5 mg orally 1 tablet / day which not related to meals.
- The optimal duration of treatment with Femara is not known. The drug should be discontinued if there is a tumor recurrence.
How to use the drug Femara
Femara drug is indicated to take 1 capsule / day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You can take this medicine with or without food.
While using Femara, you may need frequent blood tests. Your bone mineral density may also need to be checked.
Store at room temperature away from moisture and heat.

What happens if I miss a dose?
- Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
- Search to the nearest health facility or call emergency 115
Important Information
You should not use Femara if you have not completely gone through menopause.
Femara can harm an unborn baby or cause birth defects. Do not use if you are pregnant.
Before using Femara, tell your doctor if you have osteoporosis, high cholesterol, or liver disease (especially cirrhosis).
Femara may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake. To be sure Femara is helping your condition, your blood may need to be tested often. Your bone mineral density may also need to be checked. Visit your doctor often.
Tell your doctor about all other medicines you use, especially tamoxifen (Soltamox).
Before taking pills Femara
You should not use Femara if you are allergic to letrozole, or if you have:
- if you haven’t gone completely through menopause.
To make sure Femara is safe for you, tell your doctor if you have:
- liver disease (especially cirrhosis);
- osteoporosis, bone (low bone mineral density);
- high cholesterol; or
- If you also take tamoxifen.
Although it is not likely that a postmenopausal woman will become pregnant, Femara may harm an unborn baby. Do not take this medication if you are pregnant or may become pregnant. Use effective birth control if you are not past menopause, and tell your doctor right away if you become pregnant during treatment.
It is not known whether letrozole passes into breast milk or if it could harm a nursing baby. You should not breastfeed while you are using Femara.
What should i avoid while in contact with Femara?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake.
Letrozole can pass into body fluids (urine, stool, vomit). Caregivers should wear rubber gloves when cleaning a patient’s body fluids, handling contaminated waste or washing or changing diapers. Wash hands before and after removing gloves. Wash soiled clothes and towels separately from other laundry.
Femara side effects
Get emergency medical help if you have signs of an allergic reaction to Femara : hives; shortness of breath; swelling of face, lips, tongue, or throat.
Common side effects of Letrozole
- Pain in bones, joints or muscle pain
- Headache and nausea
- Sweating, coughing
- Constipation
- Shortness of breath
- Difficulty sleeping
- Weight gain
- High cholesterol
- Altered liver function tests
- Depression
- Hair loss or baldness
- Swelling in the feet, ankles and lower legs
Severe side effects of Letrozole
You should stop using this medicine and call your doctor if you experience any of the following serious side effects:
- Allergic reactions, including life-threatening allergic reactions
- Brittle bones and fractures
- Heart attack, stroke, blood clotting and high blood pressure
- Uterine cancer
What other drugs will affect Femara?
- Other drugs may interact with letrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
- Concomitant use with caution: The drug tends to depend mainly on isoenzymes (cytochrome P450 isozyme 2A6, 2C19, CYP2A6) & drugs with a narrow therapeutic index.

Source: index-china.com
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Note: Information about the article about Femara 2.5mg Letrozole for the purpose of sharing knowledge for reference only, the patient is not allowed to use the medication on his own, all information on drug use must be under the direction of a qualified physician. .
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Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Pharmacy.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Medical Certificate:
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.
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