Bonviva medicine 150mg ibandronic treat postmenopausal osteoporosis

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Bonviva medicine 150mg ibandronic treat postmenopausal osteoporosis

• Brand Name: Bonviva 150mg (Boniva)
• Active ingredient: ibandronic acid
• Manufacturer: Roche
• Content: 150 mg 
• Package: Box of 3 tablets
• Treatment: osteoporosis, after menopause 
• Pharmacological group: Drugs used to treat bone diseases 
• Ibandronic Medication Prices: COMMENT below for prices OR Click on the link: https://thuoclp.com/chatFB type “Bonviva”

Bonviva medicine 150mg ibandronic acid 

• The drug Bonviva is a medicine that contains active ibandronic acid. It is available as tablets (150mg) and as a solution for injection in a prefilled syringe (3 mg).

Drug Bonviva 150mg is used to treat what disease? Using bonviva treatment for how long

• Bonviva is used to treat osteoporosis (a disease that makes bones fragile) in women who have gone through menopause and are at risk of developing developing fractures (breaks).
• Its effect in reducing the risk of spine fractures has been demonstrated in studies, but its effect on the risk of femoral neck fractures (the top of the femur) has not been established.
• The drug is only sold and used as directed.

What must you consider before using ibandronic bonviva 150mg?

Do not take Bonviva pills

• If you are allergic (hypersensitive) to ibandronic acid, or to any other ingredients of Bonviva.
• If you have certain problems with your esophagus (tube that connects your mouth to your stomach) like narrowing or difficulty swallowing.
• If you are unable to stand or sit upright for at least one hour (60 minutes) at a time.
• If you have, or in the past low blood calcium. Please consult your physician.
• Children and teens

Special care with Bonviva

Some people need to be especially careful while they take Bonviva. Check with your doctor:

• If you have any mineral metabolism disorders (such as vitamin D deficiency).
• If your kidneys are not working properly.
• If you have any swallowing or digestive problems.
• If you are undergoing dental treatment or going through dental surgery, tell the dentist that you are being treated with Bonviva.
• Stimulation, inflammation or ulcers of the esophagus (tube that connects your mouth to your stomach) often have symptoms of severe chest pain, severe pain after swallowing food and / or drink, severe nausea or vomiting, especially is if you do not drink a full glass of water and / or if you lie down within an hour after taking Bonviva.
• If you develop these symptoms, stop taking Bonviva and tell your doctor right away.

Use other medications

• Please tell your doctor or pharmacist if you are taking, or have recently used any other medicines, including medicines obtained without a prescription. Especially:
• The supplements contain calcium, magnesium, iron or aluminum, as they may affect the effects of Bonviva.
  Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) (including ibuprofen, diclofenac sodium and naproxen) can irritate the stomach and intestines. Bisphosphonates (like Bonviva) can do the same. So be especially careful if you take painkillers or anti-inflammatory drugs while you are taking Bonviva.
• After swallowing your Bonviva pill monthly, wait for 1 hour before taking any other medicines, including indigestion, calcium or vitamin supplements.

Drink Bonviva with food and drink

Do not take Bonviva with food. Bonviva will be less effective when taken with food.
You can drink plain water but no other drinks

Pregnancy and lactation

Do not take Bonviva if you are pregnant or breastfeeding. If you are breastfeeding, you may need to stop to drink Bonviva.
Ask your doctor or pharmacist for advice before taking any medicine.

Drive and use machines

You can drive and use machines because it is unlikely that Bonviva will affect your ability to drive and use your machine.

How to use ibandronic bonviva 150mg medicine effectively 

• Bonviva is available as a tablet orally or as a solution for intravenous infusion. 
• In tablet form: the dose is 1 tablet / month, taken on the same day every month. Should drink 1 hour before eating with plenty of water. (In areas with hard water, where tap water contains lots of dissolved calcium, bottled water with a low mineral content may be used.) Patients should not lie down for one hour after taking the medication. 
• Intravenous form: The dose by injection is 3 mg 1 time every 3 months. Patients taking Bonviva should also take vitamin D and calcium supplements if they do not get enough from their diet.

What is the mechanism of action of ibandronic bonviva 150mg?

• Osteoporosis occurs when not enough new bone grows to replace bones that are naturally broken down. Gradually, the bones become thin and fragile, and more likely to break. Osteoporosis is more common in women after menopause, when levels of the female hormone estrogen decrease, because estrogen helps keep bones strong.
• The active substance in Bonviva, ibandronic acid, is a bisphosphonate. It stops the action of osteoclasts, the cells involved in disrupting bone tissue. Preventing the action of cells leads to less bone loss.

Studies on ibandronic bonviva 150mg to treat osteoporosis

Bonviva has been studied in 3 main studies involving women with osteoporosis. 

• The first study compared Bonviva tablet 2.5 mg once daily for placebo (a dummy treatment) in nearly 3,000 women and looked at how many new spine fractures were seen in patients within three years . 
• Two other studies compared monthly 150 mg Tablets (1,609 patients) and injection (1,395 patients) with 2.5 mg once daily. Studies have looked at changes in bone density in the spine and hip over two years.
• 2.5 mg once daily medication used in the study was discontinued.

What are the benefits of Bonviva medicine during studies?

• In the first study, daily treatment with Bonviva tablet 2.5 mg reduced the risk of new spine fractures by 62% compared to placebo. 
• Two other studies show that taking 150 mg monthly tablets and injections are more effective than 2.5 mg once a day on increasing bone density in the spine and hip. 
• Over two years, bone density in the spine increased by 7% with monthly tablet and 6% with injection, compared with 5% with daily tablet. At the hip, bone density increased by 4% with the monthly tablets and 3% with the injections, compared with 2% with the oral tablet form daily.

Undesirable effects during the use of ibandronic bonviva 150mg medication 

• The most common side effects with Bonviva (seen in 1 to 10 patients within 100) are joint pain (joint pain) and flu (flu) -like symptoms. 
• The most serious side effects with Bonviva are anaphylactoid reactions (severe allergic reactions), atypical fractures of the femur (a type of muscular fracture of the bone of the upper leg), bone necrosis jaw (damage to the bones of the jaw, which can lead to pain, sores in the mouth or loose teeth), digestive (stomach and intestines) irritation and eye inflammation. For a complete list of all side effects reported with Bonviva, please see the package leaflet.
• Bonviva is not used in patients with hypocalcaemia (low blood calcium levels). Candles are not used in patients with esophageal abnormalities or who cannot stand or sit upright for at least an hour. For a complete list of restrictions with Bonviva, please see the package leaflet.

Reputable source: https://thuoclp.com/san-pham/thuoc-bonviva-150mg-ibandronic-dieu-tri-loang-xuong-sau-man-kinh/

Why was Bonviva approved?

• The Commission for Human Medicines Use (CHMP) decides that Bonviva’s benefits outweigh risks and recommends that it be authorized marketing.

What measures are being taken to ensure safe and effective use of Bonviva?

• A risk management plan has been developed to ensure that Bonviva is used as safely as possible. 
• Based on this plan, safety information has been included in the summary of product specifications and package leaflets for Bonviva, including appropriate precautions to be followed by care professionals. Healthcare and patients.
• In addition, the marketing company Bonviva will provide a card to notify patients receiving Bonviva about the risk of osteonecrosis of the jaw and instruct them to contact their doctor if they have symptoms.

Notes on the use of ionicronic bonviva 150mg medicine

• Correct bone or mineral metabolism disorders first, maintaining adequate levels of calcium and vitamin D.
• CKD; Monitor renal function, serum calcium, phosphate and magnesium. Heart disease; avoid dehydration. The risk of osteoarthritis is rare; provide warning cards and advise patients to maintain good oral hygiene, participate in periodic dental examinations, avoid dental invasions and report dental symptoms.
• Ensure dental problems are resolved before starting treatment. Rare risk of bone degeneration of the outer ear canal; Advise patient to report earache, discharge, or infection.
• The risk of atypical femoral fractures is rare; Advise patients to report pain in the thighs, hips or groin.
• In addition, GI disorders on; warn patients about the risk of esophageal problems, especially if they do not take the correct dose and report any symptoms such as difficulty swallowing, back pain, heartburn worse. Stop immediately if happened.

How long is the bonviva 150mg used for ibandronic acid?

It is important to continue taking Bonviva every month, as long as your doctor prescribes medication for you. Bonviva can only treat osteoporosis as long as you continue to take it.

If you take too much Bonviva

If you mistakenly take many pills, drink a full glass of milk and talk to your doctor right away.

Don’t make yourself vomit, and don’t lie down? This can cause Bonviva to irritate your esophagus.

If you forget a dose

If you forget to take your tablet the morning of the day of your choice, do not use it at the end of the day. Instead, consult your calendar and find out when your next dose is:

If your next scheduled dose is only 1 to 7 days?

You should wait until the next scheduled dose is due and take it as usual; Then, continue using a tablet once a month on the scheduled days you have marked on your calendar.

If your next scheduled dose is more than 7 days?

You should take one pill the next morning after the day you remember, then continue taking one pill once a month on the scheduled days you have marked on your calendar.

Never take two Bonviva tablets in the same week.

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