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Aromasin is indicated for adjuvant treatment of postmenopausal estrogen receptor (estrogen-receptor) positive or unknown early breast cancer in order to reduce the risk of breast cancer recurrence (widespread and regional). cancer) and opposite breast cancer.
Aromasin medicine 25mg Exemestane treats breast cancer
- Brand name: Aromasin 25mg
- Active ingredient: Exemestane
- Manufacturer: PFizer
- Content: 25 mg
- Form: Tablets
- Package: Box of 30 tablets
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What is Aromasin 25mg Exemestane?
- Exemestane is also called Aromasin. It is a hormone treatment drug called aromatase inhibitor and is used to treat breast cancer. It is only suitable for postmenopausal women
- Many breast cancers are stimulated to develop by the female sex hormones estrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of hormones.
- In their postmenopausal women, estrogen is produced primarily by changing androgens (sex hormones produced by the adrenal glands) into estrogen. This process is called aromatization and occurs primarily in adipose tissue, muscle and skin. It needs a special enzyme called aromatase.
- In early breast cancer, taking exemestane can help prevent breast cancer from recurring. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
How to use the drug exemestane 25mg how ?
- Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
- Exemestane is usually taken once daily, after a meal. Try to take the medication at the same time every day.
- While using exemestane, you may need frequent blood tests.
- Use exemestane regularly to get the most benefit. Get your prescription refilled before you run out of medication completely. You may need to keep taking this medication for up to 5 years.
- Store in original container at room temperature away from moisture and heat.
Information dose of the drug exemestane 25 mg
Usual adult dosage for breast cancer:
25 mg orally once a day
Comments: The drug should be taken after meals.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Find the nearest health facility or call emergency 115
Uses
- Adjuvant treatment of postmenopausal women with aggressive early-stage estrogen receptor breast cancer has received 2-3 years of tamoxifen and is transitioning to exemestane complete a total of five consecutive years of hormone adjuvant therapy.
Treatment of advanced breast cancer in postmenopausal women with advanced disease after tamoxifen therapy.
About aromasin side effects
We have listed the side effects related to exemestane below. You can use the link to learn more about each side effect.
You may have 1 or 2 or a few side effects. They may be mild or worse. A side effect may get better or worse through your treatment course, or more side effects may develop as the course goes on. It depends on how many times you have taken it before, your general health, the amount of medicine you have (the dose), the other medicines you are taking.
Tell your doctor or nurse right away if any of the side effects get serious.
Common side effects
More than 10 out of 100 people have one or more effects.
- Hot flashes and sweating – this will happen in more than 1 in 5 women (22%)
- joint or muscle pain – this happens within 1 in 5 women (18%)
- Fatigue (fatigue) – this happens in about 1 in 6 women (16%)
- Feeling or being sick – this is usually mild and can be easily controlled with anti-illness tablets. It affects more than 1 in 10 women (12%)
- Difficulty sleeping (insomnia) – more than 1 in 10 women have this
- Hair thinning affects more than 1 in 10 women
- Headache
Frequent side effects
Between 1 and 10 out of 100 people have one or more of these.
- Loss of appetite
- Interest rates go down during sex
- Stomachache
- indigestion
- Skin rashes – these are usually mild. Tell your doctor or nurse if you have a rash. This happens in about 1 in 10 women taking exemestane (10%)
- Feeling dizzy – about 1 in 10 women (10%) have some dizziness. Do not drive or operate machinery if you have this
- Feeling very sad, including depression
- Loss of bone strength – this is due to a lack of estrogen over long periods of time and bones can break down more easily. You should have a DEXA scan to check your bone density before you start treatment
- Diarrhea or constipation – if this happens it is usually mild. You should drink a lot of water.
- Vaginal bleeding occurs in less than 1 in 20 women (5%) – this mostly happens during the first few weeks of treatment when the woman has changed from one type of hormone therapy to another. Tell your doctor or nurse if blood flow continues
- Swelling in hands and feet caused by an accumulation of fluid
- Carpal tunnel syndrome – tell your doctor or nurse if you have any pain, tingling or weakness in your hands
Side effects are rare
Less than 1 in 100 people has the effect.
- Asleep
- Muscle weakness
- Hepatitis – tell your doctor right away if you feel unwell, or have jaundice and eyes, itching, abdominal pain on the right hand side, and loss of appetite
Important points to remember
Talk to your doctor, pharmacist or nurse about all your side effects so they can help you manage them. You should have a contact number for the chemotherapy nurse, clinic or ward nurse. You can call if you have any questions or problems. They can give you advice or reassure you. If in doubt, call them.
Pregnancy and birth control
- This medicine may harm a developing baby in the womb. It is important not to get pregnant while you are having treatment with this medication and for a few months later. Talk to your doctor or nurse about effective birth control before starting treatment.
Breastfeeding
- Do not breastfeed during treatment because the drug can pass in breast milk.
Road intolerance
- Exemestane contains small amounts of sucrose (a type of sugar). Tell your doctor if you have an intolerance for any type of sugar.
What are the things to know about exemestane?
- You should not use exemestane if you have not started menopause, or if you are pregnant or may be pregnant.
- Do not use exemestane if you are pregnant. It can harm an unborn baby.
What information should I give to my doctor when taking exemestane?
You should not use exemestane if you are allergic to it, or:
- if you are pregnant or may be pregnant; or
- if you haven’t finished menopause, and you’re still having your period.
To make sure exemestane is safe for you, tell your doctor if you have:
- liver failure; or
- kidney disease.
Exemestane may reduce bone mineral density, which may increase the risk of developing osteoporosis. Talk to your doctor about your individual risk of bone loss.
Although it is not likely that a postmenopausal woman will become pregnant, exemestane may cause birth defects. Do not take this medication if you are pregnant or may become pregnant. You may need to have a negative pregnancy test before starting this treatment.
If you have not past menopause, use effective birth control to prevent pregnancy while you are taking exemestane and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant while taking exemestane.
It is not known whether exemestane passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using this medication.
What should i avoid while taking exemestane?
This drug can pass into body fluids (urine, stool, vomit). Caregivers should wear rubber gloves when cleaning a patient’s body fluids, handling contaminated waste or washing or changing diapers. Wash hands before and after removing gloves. Wash soiled clothes and towels separately from other laundry.
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake.
Drug interactions
What drugs may interact with exemestane?
Drug interactions can alter the ability of the drug to work or increase the effects of side effects. This document does not include the full range of possible drug interactions. It is best to write down a list of all the medications you are currently taking (including prescription drugs, nonprescription drugs, and supplements) to show to your doctor or pharmacist. You should not use, stop, or change the dosage of your medication without your doctor’s permission.
- Carbamazepine;
- ENZALUTAMIDE;
- Fosphenytoin;
- Idelalisib;
- Mitotane;
- Nilotinib;
- Phenobarbital;
- Phenytoin;
- Primidone;
- Rifabutin;
- Rifampin;
- Rifapentine;
- St. Herbs John’s.
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