Arimidex medicine 1mg Anastrozole treats breast cancer

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Arimidex medicine 1mg Anastrozole treats breast cancer

• Brand name: Arimidex 1mg
• Active ingredient: Anastrozole
• Manufacturer: Astrazeneca
• Content: 1mg
• Form: Tablets 
• Package: Box of 28 tablets
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Assign arimidex 1mg anastrozole drug 

• Adjuvant treatment for postmenopausal women with early-stage estrogen receptor-positive breast cancer.
• Treatment of advanced breast cancer in postmenopausal women. The efficacy has not been demonstrated in patients with negative estrogen receptors unless clinical response to tamoxifen has been previously reported.
• Adjuvant treatment for postmenopausal women with estrogen-positive early-stage breast cancer, patients who have received tamoxifen support therapy for 2 to 3 years.

Benefits of the Arimidex drug

ATAC research shows that 5 years of Arimidex is better than 5 years of tamoxifen as the first hormone therapy for postmenopausal women with hormone receptor-positive breast cancer at an early stage. Arimidex is better than tamoxifen for:

• Increasing the time before cancer returns in people who have relapsed
• reduce the risk of cancer spreading to other parts of the body
• reduce the risk of new breast cancer developing

The research presented at the San Antonio Breast Cancer Symposium 2013 shows:

• Arimidex may reduce the risk of hormone receptor-positive breast cancer for the first time in post-menopausal high-risk women.
• Arimidex is not FDA approved for this use, but doctors may consider it a good alternative to other approved hormone therapies to reduce the risk in high-risk women.

How Arimidex works

• Arimidex is a strong and selective non-steroidal aromatase inhibitor. In postmenopausal women, estradiol is produced primarily from the conversion of androstenedione to estrone through the aromatase enzyme complex in peripheral tissues. Estrone is then converted to estradiol.
• Reduced levels of circulating estradiol have been shown to work well in women with breast cancer. In postmenopausal women, Arimidex at a dose of 1 mg daily produces estradiol inhibition greater than 80% by using a very sensitive test.

Arimidex is contraindicated 

Hypersensitivity to the drug component. Premenopausal women. Pregnant & lactating women. Renal impairment (ClCr 20mLmin). Moderate or severe liver disease. Are taking tamoxifen or estrogen-containing therapy.

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What is arimidex? What medication is anastrozole?

• Arimidex (anastrozole) reduces estrogen levels in postmenopausal women, which can slow the growth of certain types of breast tumors that require estrogen to grow in the body.
• Arimidex is used to treat breast cancer in postmenopausal women. It is often used for women with advanced cancer even after taking tamoxifen (Nolvadex, Soltamox).
• Arimidex may also be used for purposes not listed in this medication guide.

Important information Arimidex drug

• Do not use Arimidex if you are pregnant. It can harm an unborn baby.
• Arimidex may not work as well if you take it with estrogen pills (such as hormone replacement therapy, estrogen cream or birth control pills, injections, implants, skin patches and vaginal rings).
• Arimidex may increase your risk of stroke or blood clot. Call your doctor right away if you experience sudden numbness or pain, especially on one side of your body, sudden headache, speech problems, or vision or balance problems.

Before taking Arimidex 1mg Anastrozole

You should not use Arimidex if you are allergic to anastrozole, if you breastfeed, or if you are not yet menopausal. Arimidex is not for men or children.

To make sure Arimidex is safe for you, tell your doctor if you:

• heart disease;
• circulation problems;
• history of stroke or blood clot;
• severe liver disease;
• high cholesterol; or
• osteoporosis or low bone density.

Arimidex may reduce bone mineral density, which may increase the risk of osteoporosis. Your bone mineral density may need to be checked before and during treatment with anastrozole.

Although it is unlikely that menopausal women will become pregnant, anastrozole can harm an unborn baby. Do not take this medication if you are pregnant or may be pregnant. Use effective birth control if you are not menopausal, and tell your doctor right away if you become pregnant during treatment.

It is not known whether anastrozole can pass into breast milk if it could harm a nursing baby. You should not breast-feed while you are using Arimidex.

You may need to get tested before using Arimidex, to make sure you are not pregnant.

How to use Arimidex?

Dosage: Adults, including the elderly 1 mg once daily.

• Arimidex is usually taken once daily. Follow all directions on your prescription medication label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
• You can take Arimidex with or without food.
• You may need to continue taking this medicine for up to 5 years. Follow the doctor’s instructions.
• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

• Seek immediate medical attention or call 115

What should i avoid?

• Anastrozole can be transmitted through body fluids (urine, stool, vomiting). Caregivers should wear rubber gloves while cleaning a patient’s body fluids, handling garbage or washing clothes or changing diapers. Wash hands before and after removing gloves. Wash soiled clothes and linen separately from other laundry.
• This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Arimidex Medication Side Effects

Get emergency medical help if you have signs of allergy to Arimidex: rash; shortness of breath; swelling of face, lips, tongue, or throat.

Call your doctor at once if you:

• shortness of breath (even with mild exertion), swelling, rapid weight gain;
• a bone crack;
• Inflammation;
• liver problems – nausea, stomach pain, itching, fatigue, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• signs of a stroke – sudden numbness or weakness (especially on one side of the body), sudden headache, slurred speech, vision or balance problems; or
• severe skin reaction – fever, sore throat, swelling of the face or tongue, burning in the eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blisters skin.

Common Arimidex side effects may include:

• weakness, hot flashes;
• numbness or gentle feeling on the skin;
• swelling of the ankles or feet;
• joint pain or stiffness, problems with your fingers while holding;
• sore throat, headache, back pain, bone pain;
• depression, mood changes, sleep problems (insomnia);
• high blood pressure (severe headache, blurred vision, tightness in the neck or ears);
• vomiting and vomiting; or
• mild rash.

Other drug interactions with Arimidex

Tell your doctor and pharmacist all medicines you are taking.

This includes all prescription, over-the-counter medicines, vitamins, nutritional supplements (nutritional shakes, protein powders, etc.), herbal remedies and any illegal or recreational drugs .

You should avoid taking the following medicines with Arimidex:

• DHEA supplementation (dihydroepiandrosterone)
• Soltamox (tamoxifen)
• Any medications that contain estrogen like birth control pills and hormone replacement therapy medications
• Warfarin ( Coumadin , Jantoven)

Arimidex can slow down the absorption of other drugs, which can dangerously raise the concentration of other drugs in the blood.

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Interact with food

Interacting with alcohol

• Drinking alcohol while taking Arimidex can cause nausea, diarrhea and vomiting. You should avoid or limit alcohol consumption while taking this medication.

Interact with grapefruit

• Taking Arimidex with grapefruit slows down the body’s ability to process certain medications. You should avoid grapefruit and grapefruit juice when using Arimidex.

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