What is Nivalin?
Nivalin medicine is used to treat mild to moderate dementia (memory loss and mental changes) that is a sign of Alzheimer’s disease.
The drug will not cure Alzheimer’s disease, and it will not prevent it from getting worse. However, Nivalin may improve thinking ability in some patients with Alzheimer’s disease.
In Alzheimer’s disease, many chemical changes take place in the brain. One of the earliest and biggest changes was having less of a chemical called acetylcholine (ACh). ACh helps the brain function properly. The drug slows down the breakdown of ACh, so it can build up and have a greater effect.
However, as Alzheimer’s disease gets worse, the amount of ACh becomes less and less, so drug may not work as well.
Drug information Nivalin
- Ingredients of the drug Nivalin: Galantamine.
- Registration Number: VN-22371-19.
- Group: Psychoactive drugs
- Packaging: Box of 20 tablets.
- Production Company: Sopharma AD – Bun Ga Ri Company.
Indications for the use of drug
Nivalin is used to treat mild to moderate dementia (mental function problems) associated with Alzheimer’s disease.
The drug can be used as part of combination therapy. That means you need to take it with other medicines to treat Alzheimer’s-related dementia.
What is the dose of Nivalin ?
The information provided is not a substitute for medical professional advice. Always consult your doctor or pharmacist before deciding to take a medication.
For Alzheimer’s disease the daily dose is: 5mg / time, 2 times / day. Maintain for 4 weeks, then the dose can be increased to 10mg/time, 2 times/day. The dose is increased depending on the individual patient’s response. Increase the dose only if directed by your doctor.
How to take Nivalin
Take this medication by mouth with food, usually twice daily at breakfast and in the evening, or as directed by your doctor. Drink plenty of fluids with this medicine unless otherwise directed.
If you stop taking Nivalin for longer than 3 days, your doctor may direct you to start it again at a low dose and gradually increase your dose to reduce your risk of side effects. Carefully follow your doctor’s instructions.
Use this medicine regularly to get the most benefit from it. Do not stop taking or increase the dose unless directed to do so by your doctor.
It may take at least 4 weeks of continued use before the full benefits of this medicine take effect.
Contraindications to the use of the drug
Do not give drug to a patient who is allergic to Galantamine or to any of the other ingredients in this medicine.
Nivalin side effects
The most common side effects that occur with Nivalin include:
- Decreased appetite;
- Weight loss.
If these effects are mild, they may go away in a few days or weeks. If they get worse or don’t go away, talk to your doctor or pharmacist.
What drugs can interact with Nivalin ?
Tell your doctor about all your current medicines and any you start or stop using, especially:
- cold or allergy medicine that contains an antihistamine (benadryl and others);
- Drugs for the treatment of Parkinson’s disease;
- Medicines to treat excess stomach acid, stomach ulcers, motion sickness or irritable bowel syndrome;
- Bladder or urinary medicines: darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;
- Bronchodilators: aclidinium, ipratropium, or tiotropium .
This list is not exhaustive. Other drugs may interact with galantamine, including prescription and over-the-counter medicines, vitamins, and herbal products.
Precautions while using Nivalin
Bladder problems: Nivalin may make it more difficult to empty the bladder and may contribute to urinary tract problems. If you have bladder problems or a history of urinary tract problems, discuss with your doctor how this medication may affect your condition.
Reduced alertness: Nivalin may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other hazardous jobs until you have determined how this medicine affects you.
Gender: Women are more likely to experience side effects such as nausea and vomiting. This is also more likely to happen in women who are underweight.
Heart disease: Nivalin can slow your heart rate, affecting people with congestive heart failure (CHF) or coronary heart disease (CAD). If you have heart disease, including blood pressure problems, discuss with your doctor how this medicine may affect your condition.
Kidney function: If you have kidney disease or decreased kidney function, discuss with your doctor how this medicine may affect your condition.
Liver function: If you have liver disease or decreased liver function, discuss with your doctor how this medicine may affect your condition.
Lung disease: Nivalin may worsen symptoms of breathing problems, such as asthmatic emphysema or chronic obstructive pulmonary disease (COPD) and bronchitis . If you have asthma, COPD, or any other breathing problem, discuss with your doctor how this medicine may affect your health.
Seizures: An increase in seizures has been reported by people taking Nivalin. It is not clear if this is due to medication or Alzheimer’s disease. If you have or are having a seizure disorder, discuss with your doctor how this medicine may affect your health.
Stomach ulcers: Medicines can increase the amount of acid produced by the stomach, increasing the risk of stomach ulcers. If you have or have ever had stomach problems or are taking nonsteroidal anti-inflammatory drugs (NSAIDs), you are at increased risk of stomach problems while taking this medicine.
Weight loss: People who take Nivalin may experience significant weight loss. In some cases, this weight loss is unhealthy and can cause other health problems. Tell your doctor about any weight loss that occurs.
Pregnancy: This medicine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medicine, contact your doctor immediately.
Breast- feeding: It is not known whether Nivalin passes into breast milk. If you are a nursing mother and are using this medicine, it may affect your baby. Talk to your doctor about whether you should continue breastfeeding.
Children: The safety and effectiveness of this medication have not been established in children. The drug is not intended for children.
Elderly: People over 85 years of age may be at greater risk of severe weight loss while taking drug.
How to store medicine?
- Store the medicine at room temperature below 30°C. Keep away from moisture and direct light.
- Keep medicine in a safe place, out of reach of children and pets.
The above article is for reference only and is not a substitute for medical diagnosis or treatment. Readers should only follow the instructions of the doctor who is treating you,Index-China disclaims responsibility if problems occur.
Reputable source ThuocLP Vietnamese: Nivalin medicine: Uses, dosage and usage
Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Pharmacy.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.