Glucosamine treats osteoarthritis and arthritis. index-china is the address of buying and selling Glucosamine medicine in Ho Chi Minh City, Hanoi, Da Nang, Can Tho … and nationwide.
Glucosamine includes the types found in nutritional supplements: Glucosamine sulfate, Glucosamine hydrochloride and N-acetyl-glucosamine.
What is glucosamine?
- Glucosamine is a natural component of cartilage, a substance that prevents bones from rubbing together and causing pain and inflammation. It can also help prevent cartilage breakdown that may occur with arthritis.
- In the supplement form Glucosamine, made from shellfish or prepared in the laboratory, is a natural compound that is chemically classified as an amino sugar.
- There are several forms of Glucosamine including: Glucosamine sulfate, Glucosamine hydrochloride and N-acetyl glucosamine.
Uses of Glucosamine
In alternative medicine, Glucosamine can help solve the following health problems:
- High cholesterol
- Inflammatory bowel disease
- Viêm xương khớp
- Rheumatoid arthritis
- Temporomandibular joint disorder (also known as “TMD” or “TMJ”)
Glucosamine can be used as a single supplement, but it is most commonly combined with other supplements, especially Chondroitin, a protein that comes from shark or cow cartilage.
The mechanism of action of Glucosamine
Glucosamine is found naturally in your body. It plays an important role in creating glycosaminoglycan and glycoprotein, which are essential building blocks of many parts of the joints, including ligaments, tendons, cartilage and synovial fluid. It is thought that the way these parts of the joints are built and maintained contributes to the development and progression of osteoarthritis.
Animal studies have found that glucosamine delivery can delay cartilage breaking as well as regenerate it.
Dosage and usage of Glucosamine
There is no standard recommended dose for this medication. Glucosamine is available without a prescription.
Supplements are often sold in capsules and capsules, and are often accompanied by other supplements that may be effective for pain relief.
For osteoarthritis, the following doses have been studied:
- Oral tablet: 1,500 mg once daily, two 750 mg doses or three 500 mg doses
- Topical cream: A cream containing 30 mg / gram of glucosamine sulfate, 50 mg / gram of chondroitin sulfate, 140 mg / gram of chondroitin sulfate is applied to the skin as needed for 8 weeks.
- Injection: 400 mg of glucosamine sulfate is injected into the muscle twice weekly for 6 weeks.
Information Glucosamine products
Glucosamine supplements are sold as: Glucosamine sulfate, Glucosamine hydrochloride and N-acetyl-glucosamine . Most studies showing benefits have used glucosamine sulfate, but there is no clinical evidence to support the use of N-acetyl glucosamine in the treatment of arthritis.
Glucosamine is often combined with chondroitin sulfate, a naturally occurring molecule in cartilage. Chondroitin gives cartilage elasticity and is thought to prevent cartilage destruction by enzymes. In some cases glucosamine is also combined with methylsulfonylmethane (or MSM) in nutritional supplements.
Imaging drug Glucosamine sulfate
Glucosamine hydrochloride drug picture
N-acetyl-glucosamine drug image
Warnings and precautions when using Glucosamine
- Diabetes: Glucosamine should be used with caution in patients with a known history of diabetes due to an increased risk of changes in blood glucose levels.
- Hyperlipidemia: Glucosamine should be used with caution in patients with a history of hyperlipidemia due to an increased risk of worsening the patient’s condition.
- Use in children: Glucosamine is not recommended for use in children and adolescents because the safety and effectiveness of its use have not been clinically established.
Side effects of Glucosamine
When used in appropriate amounts, Glucosamine sulfate appears to be safe. Oral glucosamine sulfate may cause:
- Skin reaction
Because Glucosamine products can be obtained from the shells of shellfish, there is concern that supplements may cause an allergic reaction in people with shellfish allergies.
Glucosamine can aggravate asthma.
Glucosamine sulfate may affect your blood sugar, which can affect blood sugar control during and after surgery. Stop taking Glucosamine sulfate two weeks before you need to have surgery.
Other drug interactions with Glucosamine
Other drug interactions with Glucosamine may include:
- Acetaminophen (Tylenol): Taking Glucosamine sulfate and Acetaminophen together can reduce the effectiveness of both supplements and medications.
- Warfarin (Coumadin, Jantoven): Glucosamine alone or in combination with Chondroitin supplements may increase the effect of warfarin anticoagulants. This may increase your risk of bleeding.
Sources of references Glucosamine:
- Source Drugs.com article Glucosamine : https://www.drugs.com/mtm/glucosamine.html , updated March 18, 2019.
- Source Verywellhealth.com article The Health Benefits of Glucosamine : https://www.verywellhealth.com/the-benefits-of-glucosamine-88809 , Updated October 24, 2019 .
- Prestigious source index-china.com summarizes the article Glucosamine for treating osteoarthritis : https://index-china.com/glucosamine-treats-osteoarthritis/, updated 16/3/2020.
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Note: Information about Glucosamine article for the purpose of sharing knowledge for reference only, patients are not allowed to use the drug themselves, all information on drug use must follow the appointment of a specialized physician.
Assoc.Prof.Dr. Tran Ngoc Anh is currently Hanoi Medical University Hospital, Associate Professor, Department of Internal Medicine, Gastroenterology and Head of Department of General-Uematology of Hanoi Medical University. Consulting doctor at ThuocLP Vietnamese health.
Professional qualifications, Academic degrees – Education:
Graduated from General Practitioner System, Hanoi Medical University
Graduated with a Master degree in Internal Medicine, Hanoi Medical University
Graduated from the training program specialized in Gastrointestinal, Henri Mondor Institute Center, University of Paris 6, French Republic 1996-1997; 1999
Graduated from the training program specialized in Gastrointestinal, North Royal Sydney Hospital, Australia; 2002
Graduated from a training program specialized in chronic liver diseases, Pizza, Italy 2009
Graduated with a PhD in Gastrointestinal, Hanoi Medical University
Associate Professor, Gastroenterology, Hanoi Medical University
Training and Scientific Research:
Published more than 200 articles in domestic and international specialized journals
Editor of many monographs and participates in compiling 2 textbooks.
Guide many students and graduate students of Hanoi Medical University
Manager of many grassroots research projects
Certificate of Good Clinical Practice (GCP: 2012, 2015), Ministry of Health
Specialized certificates: General gastrointestinal endoscopy, Interventional gastrointestinal endoscopy, General gastrointestinal ultrasound, Interventional gastrointestinal ultrasound (Bach Mai BV), Chronic liver disease.