Cefuroxim medicine: Uses, dosage and usage

cefuroxim-medicine-uses-dosage-usage

What is Cefuroxim?

Cefuroxim medicine is an antibiotic used to treat bacterial infections. This drug, known as a cephalosporin antibiotic, works by stopping the growth of bacteria.

Uses of Cefuroxim

Cefuroxim is used to treat many types of bacterial infections, including serious or life-threatening forms. The drug may also be used for purposes not listed in the medication guide.

Drug information Cefuroxim

  • Active ingredient: Cefuroxim axetil equivalent.  
  • Excipients: microcrystalline cellulose, colloidal silicon dioxide, sodium carmellose, sodium lauryl sulfate, magnesium stearate, hypromellose, talc, propylene glycol, titanium dioxide, alcohol 96% enough for 1 tablet.
  • Group of antibiotics, antiviral drugs

Indications for the use of Cefuroxim

Cefuroxim is generally indicated in adults and children from 3 months of age for the treatment of the infections listed below:

  • Respiratory tract: pharyngitis, streptococcal tonsillitis, acute sinusitis, otitis media, acute bronchitis with superinfection and exacerbation of chronic bronchitis, community- acquired pneumonia ;
  • Acute otitis media;
  • Uncomplicated skin and soft tissue infections;
  • Urinary tract: cystitis, pyelonephritis; uncomplicated gonorrhea;
  • Bone and joint infections;
  • Meningitis; early Lyme disease;

In addition, Cefuroxim is also indicated for the prevention of infection during surgery. Other infections as prescribed by the doctor.

Contraindications to the use of Cefuroxim

  • Allergy to the active substance or to any of the excipients in Cefuroxim.
  • The patient has been allergic to cephalosporin antibiotics before (antibiotics such as Cefuroxim, cefaclor , cefpodoxim, cefixime , cefdinir …)
  • Have a history of severe allergic reaction (anaphylaxis) to any other betalactam antibiotic.

What is the dose of Cefuroxim?

Dosage of Cefuroxim for adults

Usual Adult Dose for Bronchitis:

250-500mg orally twice a day or 750mg-1.5g IM or IV every 8 hours for 5-10 days.

Usual Adult Dose for Cystitis:

If you have no complications, take 20mg orally twice a day or give 750mg IM or IV every 8 hours for 7 to 10 days.

Usual Adult Dose for Epiglottitis:

Administer 1.5g intravenously every 6-8 hours for 7-10 days, depending on the nature and extent of the infection.

Usual Adult Dose for Joint Infection:

Administer 1.5g intravenously every 8 hours and treat continuously for about 3-4 weeks, depending on the nature and severity of the infection. If you are taking Cefuroxime to treat infections of the joints of the feet or prostheses, the treatment period may be 6 weeks or more. In addition, prostheses are often required to be removed.

Usual Adult Dose for Lyme Disease:

Take 500mg orally 2 times a day for 20 days;

The Infectious Diseases Society of America has recommended oral cefuroxime as an alternative to amoxicillin or doxycycline for the treatment of Lyme disease if oral administration is appropriate (erythema, cranial nerve palsies, first- or second-degree cardiac tamponade, and inflammation) joint). Patients with high fever should also be evaluated or treated for Human Ehrlichiosis granulocytic (HGE) and babesiosis.

Usual Adult Dose for Meningitis:

Administer 1.5g IV every 6 hours or 3g every 8 hours for 14 days.

Usual Adult Dose for Osteomyelitis:

Use 1.5g intravenously every 8 hours and treat continuously for about 4-6 weeks depending on the nature of the infection. In case of chronic osteomyelitis, you may be treated with antibiotics for an additional one to two months.

Usual adult dose for otitis media:

Take 250mg orally twice a day for 10 days.

Usual Adult Dose for Peritonitis:

Administer 750mg to 1.5g IV every 8 hours for 10-14 days;

If you have community-acquired pneumonia-associated peritonitis, administer Cefuroxime 1g per 2 liters of peritoneal dialysis, followed by a continuous maintenance dose of 150-400mg per 2 liters of dialysis.

Usual Adult Dose for Pneumonia:

If your disease is uncomplicated, give 750mg IM or IV every 8 hours;

If your disease is complicated, use 1.5g intramuscularly or intravenously every 8 hours.

When the patient has a clinical response to injection, administer 250-500 mg every 8 hours for 7 to 21 days. The duration of treatment depends on the sensitivity of the suspected pathogen to drug.

Usual Adult Dose for Pyelonephritis:

Use 750mg to 1.5g orally every 8 hours or 250-500mg, 2 times a day for 14 days, depending on the nature and severity of the infection

Usual Adult Dose for Sepsis:

Administer 1.5g intravenously every 6-8 hours, in combination with aminoglycosides;

Continuous treatment for 7-21 days depending on the nature and severity of the infection.

Usual Adult Dose for Sinusitis:

Take 250mg orally 2 times a day for 10-14 days.

Usual Adult Dose for Skin or Soft Tissue Infection:

250-500 mg orally twice a day (uncomplicated infection) or 750 mg intravenously every 8 hours for 10 days.

Usual Adult Dose for tonsillitis/pharyngitis:

Take 250mg orally 2 times a day for 10 days.

Usual Adult Dose for Upper Respiratory Tract Infection:

Take 250-500mg orally twice a day.

Usual Adult Dose for Urinary Tract Infections:

If your condition is uncomplicated, take 250mg orally twice a day for 7-10 days or give 750mg IV every 8 hours.

If your disease is complicated, give 1.5g IV every 8 hours.

Dosage of Cefuroxime for children

Usual pediatric dose for epiglottitis:

For children 3 months to 12 years of age, give 50 to 100 mg/kg IV per day in divided doses every 6-8 hours (maximum 6 g/day) for 7-10 days, depending on the nature of the child. degree of infection.

Usual Pediatric Dose for Joint Infection:

For children 3 months to 12 years, 50 mg/kg IV every 8 hours (maximum 6 g/day)

For children 13 years and older: give children the same dose as adults.

Usual Pediatric Dose for Osteomyelitis:

For children from 3 months to 12 years, use 50mg/kg IV every 8 hours (maximum 6g/day);

For children 13 years of age and older, give the child the same dose as adults.

Usual Pediatric Dose for Meningitis:

For children 3 months to 12 years old, 200-240 mg/kg IV per day in divided doses every 6-8 hours (maximum 9 g/day).

For children 13 years of age and older, give the child the same dose as adults.

Usual pediatric dose for otitis media:

For children from 3 months to 12 years: give 250 mg orally twice a day for 10 days or 15 mg/kg of fluid in the child’s ear twice a day for 10 days. The maximum daily dose of Cefuroxime is 1 g;

For children 13 years of age and older, give the child the same dose as adults.

Usual Pediatric Dose for Sinusitis:

For children from 3 months to 12 years: give 250mg orally twice a day for 10 days or 15mg/kg of fluid into the nose twice a day for 10 to 14 days. The maximum daily dose is 1g.

For children 13 years of age and older, give the child the same dose as adults.

Usual pediatric dose for infection:

For children 3 months to 12 years old, give them 15mg/kg twice a day for 10 days. The maximum daily dose is 1g.

Usual Pediatric Dose for Impetigo:

For children 3 months to 12 years old, give them 15mg/kg twice a day for 10 days. The maximum daily dose is 1g.

Usual pediatric dose for tonsillitis/pharyngitis:

For children 3 months to 12 years old, give them 10mg/kg twice a day for 10 days. The maximum daily dose is 500mg.

For children 13 years of age and older, give the child the same dose as adults.

How to take Cefuroxim

Follow all directions on your medication label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You can take the tablets with or without a meal. Do not crush the tablet or it may have an unpleasant bitter taste.

Cefuroxime oral suspension (liquid) must be taken with food.

Shake the liquid well just before you measure a dose. Measure the liquid medication with the dosing syringe provided or with a special dose-measuring spoon or medicine cup. If you do not have a dosimeter, ask your pharmacist.

If you switch from using the tablet form to using the liquid form of drug, you may not need to use the exact same dose in milligrams. This medicine may not be effective unless you use the exact form and strength that your doctor has prescribed.

Cefuroxim side effects

Get emergency medical help if you have signs of an allergic reaction: hives ; shortness of breath; swelling of the face, lips, tongue, or throat. Call your doctor right away if you have:

  • severe stomach pain, watery or bloody diarrhea;
  • Jaundice (yellowing of the skin or eyes);
  • skin rash, bruising, severe tingling or numbness;
  • Convulsions (passing or convulsions);
  • kidney problems–little or no urinating, painful or difficult urination, swollen feet or ankles, feeling tired or short of breath; or
  • severe skin reaction–fever, sore throat, swelling of the face or tongue, burning in the eyes, skin pain, then a red or purple skin rash that spreads (especially to the face or upper body) and causes blistering and flake off.

Common side effects of drug may include:

  • Diarrhea;
  • Nausea , vomiting ;
  • Unusual or unpleasant taste in your mouth; or
  • Diaper rash in infants receiving Cefuroxime liquid.

Cefuroxim interactions

Cefuroxim may interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can harm or prevent the medicine from working properly.

To avoid interactions, your doctor should carefully manage all of your medications. Be sure to tell your doctor about all medications, vitamins, or herbs you are using. To find out how this medicine might interact with something else you are taking, talk to your doctor or pharmacist.

Examples of drugs that can cause drug interactions are listed below.

Birth control pills

When taken with Cefuroxim, oral contraceptives (birth control pills) may not be well absorbed by the body. This means they may not work. Your doctor may suggest that you use another method of birth control during treatment with Cefuroxim. Examples of these drugs include:

  • drospirenone / ethyinyl estradiol
  • levonorgestrel / ethinyl estradiol
  • norethindrone acetate / ethinyl estradiol
  • desogestrel / ethinyl estradiol
  • norgestrel / ethinyl estradiol

Stomach acid medicine

When taken with certain medicines that reduce stomach acid, Cefuroxim may not be well absorbed by the body. This means it may not work. Examples of these drugs include:

antacids, such as:

  • calcium carbonate
  • magnesium hydroxide
  • Aluminum hydroxide
  • H 2 main characters , such as:
  • famotidine
  • cimetidine
  • ranitidine
  • proton pump inhibitors, such as:
  • lansoprazole
  • omeprazole
  • pantoprazole

Cefuroxime should be taken at least 1 hour before the antacid, or 2 hours after. H2 antagonists and proton pump inhibitors should be avoided during treatment with this drug.

Other drugs

Probenecid is used to treat a number of conditions, including gout and kidney stones. Taking probenecid along with Cefuroxime increases the amount of Cefuroxime in your body. This increases the risk of side effects. Your doctor will likely monitor you for side effects if you take Drug or these medicines together.

Precautions while using Cefuroxim

  • Allergy to drugs similar to Cefuroxime: If you are allergic to drugs similar to Cefuroxime, you should not take cefuroxime . An allergic reaction can be serious and in some cases it can be fatal (cause death). Talk to your doctor to find out if you’re at risk for an allergic reaction.
  • Diarrhea caused by Clostridium difficile: Using high doses of Cefuroxime, or using it for longer than 14 days, can lead to diarrhea. This diarrhea is caused by the bacteria Clostridium difficile. Usually, diarrhea is mild to moderate. In rare cases, it can lead to fatal inflammation of the colon (large intestine).
  • Phenylketonuria: Cefuroxime oral suspension contains phenylalanine. This is an amino acid that occurs naturally in many foods, such as eggs and meat. You should avoid taking this medicine if you have phenylketonuria. With this condition, the body cannot break down phenylalanine.

How to store Drug?

  • You should store medicine at room temperature, in a cool, dry place, away from direct sunlight.
  • You should not store the medicine in the refrigerator.
  • Keep the medicine out of the reach of children.
  • Do not throw medicine down the toilet or plumbing.

The above article is for reference only and is not a substitute for medical diagnosis or treatment. Readers should only follow the instructions of the doctor who is treating you, Index-China disclaims responsibility if problems occur.

Index-China

See also: https://index-china.com/cefuroxim-medicine/

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